Search on: MATRIX METALLOPROTEINASE 16 
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Descriptor English:   Matrix Metalloproteinase 16 
Descriptor Spanish:   Metaloproteinasa 16 de la Matriz 
Descriptor Portuguese:   Metaloproteinase 16 da Matriz 
Tree Number:   D08.811.277.656.300.480.525.300.600
D08.811.277.656.675.374.525.300.750
Definition English:   A transmembrane domain-containing matrix metalloproteinase. It is synthesized as an inactive zymogen that is activated by the proteolytic action of PROPROTEIN CONVERTASES. Matrix metalloproteinase 16 plays a direct role in the cleavage of proteins in the pericellular environment. In addition it can function indirectly by enzymatically activating the proprotein form of other MATRIX METALLOPROTEINASES such as the zymogen of MATRIX METALLOPROTEINASE 2. 
History Note English:   2007(2005) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   52235 
Unique Identifier:   D053513 

Occurrence in VHL:
 

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